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Multicohort study of change in job strain, poor mental health and incident cardiometabolic disease
Stockholms universitet, Samhällsvetenskapliga fakulteten, Stressforskningsinstitutet.
Stockholms universitet, Samhällsvetenskapliga fakulteten, Stressforskningsinstitutet.
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Antal upphovsmän: 152019 (Engelska)Ingår i: Occupational and Environmental Medicine, ISSN 1351-0711, E-ISSN 1470-7926, Vol. 76, nr 11, s. 785-792Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objectives Several recent large-scale studies have indicated a prospective association between job strain and coronary heart disease, stroke and diabetes. Job strain is also associated with poorer mental health, a risk factor for cardiometabolic disease. This study investigates the prospective relationships between change in job strain, poor mental health and cardiometabolic disease, and whether poor mental health is a potential mediator of the relationship between job strain and cardiometabolic disease.

Methods We used data from five cohort studies from Australia, Finland, Sweden and UK, including 47 757 men and women. Data on job strain across two measurements 1-5 years apart (time 1 (T1)-time 2 (T2)) were used to define increase or decrease in job strain. Poor mental health (symptoms in the top 25% of the distribution of the scales) at T2 was considered a potential mediator in relation to incident cardiometabolic disease, including cardiovascular disease and diabetes, following T2 for a mean of 5-18 years.

Results An increase in job strain was associated with poor mental health (HR 1.56, 95% CI 1.38 to 1.76), and a decrease in job strain was associated with lower risk in women (HR 0.70, 95% CI 0.60-0.84). However, no clear association was observed between poor mental health and incident cardiometabolic disease (HR 1.08, 95% CI 0.96-1.23), nor between increase (HR 1.01, 95% CI 0.90-1.14) and decrease (HR 1.08, 95% CI 0.96-1.22) in job strain and cardiometabolic disease.

Conclusions The results did not support that change in job strain is a risk factor for cardiometabolic disease and yielded no support for poor mental health as a mediator.

Ort, förlag, år, upplaga, sidor
2019. Vol. 76, nr 11, s. 785-792
Nyckelord [en]
mental health, cardiovascular, diabetes mellitus, stress, meta-analysis
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Identifikatorer
URN: urn:nbn:se:su:diva-176576DOI: 10.1136/oemed-2018-105595ISI: 000497712200002PubMedID: 31488605OAI: oai:DiVA.org:su-176576DiVA, id: diva2:1377495
Tillgänglig från: 2019-12-12 Skapad: 2019-12-12 Senast uppdaterad: 2019-12-12Bibliografiskt granskad

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Av författaren/redaktören
Magnusson Hanson, Linda L.Vahtera, JussiPeristera, ParaskeviLaMontagne, Anthony D.Milner, AllisonLange, TheisWesterlund, Hugo
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Stressforskningsinstitutet
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Occupational and Environmental Medicine
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi

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