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Characterization of Lu-176 background in LSO-based PET scanners
Stockholms universitet, Naturvetenskapliga fakulteten, Fysikum. Siemens Healthcare Molecular Imaging, USA; Karolinska Institute, Sweden; University of Tennessee, USA.
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Rekke forfattare: 72017 (engelsk)Inngår i: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 62, nr 9, s. 3700-3711Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

LSO and LYSO are today the most common scintillators used in positron emission tomography. Lutetium contains traces of Lu-176, a radioactive isotope that decays beta(-) with a cascade of. photons in coincidence. Therefore, Lutetium-based scintillators are characterized by a small natural radiation background. In this paper, we investigate and characterize the Lu-176 radiation background via experiments performed on LSO-based PET scanners. LSO background was measured at different energy windows and different time coincidence windows, and by using shields to alter the original spectrum. The effect of radiation background in particularly count-starved applications, such as Y-90 imaging, is analysed and discussed. Depending on the size of the PET scanner, between 500 and 1000 total random counts per second and between 3 and 5 total true coincidences per second were measured in standard coincidence mode. The LSO background counts in a Siemens mCT in the standard PET energy and time windows are in general negligible in terms of trues, and are comparable to that measured in a BGO scanner of similar size.

sted, utgiver, år, opplag, sider
2017. Vol. 62, nr 9, s. 3700-3711
Emneord [en]
LSO background, randoms, PET
HSV kategori
Identifikatorer
URN: urn:nbn:se:su:diva-143445DOI: 10.1088/1361-6560/aa68caISI: 000399098700001PubMedID: 28333041OAI: oai:DiVA.org:su-143445DiVA, id: diva2:1106486
Tilgjengelig fra: 2017-06-07 Laget: 2017-06-07 Sist oppdatert: 2017-06-07bibliografisk kontrollert

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