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Childhood social class and cognitive aging in the Swedish Adoption/Twin Study of Aging
Stockholms universitet, Samhällsvetenskapliga fakulteten, Centrum för forskning om äldre och åldrande (ARC), (tills m KI).
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Antal upphovsmän: 72017 (Engelska)Ingår i: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 114, nr 27, s. 7001-7006Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

In this report we analyzed genetically informative data to investigate within-person change and between-person differences in late-life cognitive abilities as a function of childhood social class. We used data from nine testing occasions spanning 28 y in the Swedish Adoption/Twin Study of Aging and parental social class based on the Swedish socioeconomic index. Cognitive ability included a general factor and the four domains of verbal, fluid, memory, and perceptual speed. Latent growth curve models of the longitudinal data tested whether level and change in cognitive performance differed as a function of childhood social class. Between-within twin-pair analyses were performed on twins reared apart to assess familial confounding. Childhood social class was significantly associated with mean-level cognitive performance at age 65 y, but not with rate of cognitive change. The association decreased in magnitude but remained significant after adjustments for level of education and the degree to which the rearing family was supportive toward education. A between-pair effect of childhood social class was significant in all cognitive domains, whereas within-pair estimates were attenuated, indicating genetic confounding. Thus, childhood social class is important for cognitive performance in adulthood on a population level, but the association is largely attributable to genetic influences.

Ort, förlag, år, upplaga, sidor
2017. Vol. 114, nr 27, s. 7001-7006
Nyckelord [en]
childhood social class, cognitive aging, adoption, twins
Nationell ämneskategori
Annan naturvetenskap Gerontologi, medicinsk/hälsovetenskaplig inriktning
Identifikatorer
URN: urn:nbn:se:su:diva-145995DOI: 10.1073/pnas.1620603114ISI: 000404576100053OAI: oai:DiVA.org:su-145995DiVA, id: diva2:1136673
Tillgänglig från: 2017-08-29 Skapad: 2017-08-29 Senast uppdaterad: 2018-09-07Bibliografiskt granskad

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Fors, Stefan
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Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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Proceedings of the National Academy of Sciences of the United States of America
Annan naturvetenskapGerontologi, medicinsk/hälsovetenskaplig inriktning

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