Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Asymmetric Synthesis of Alkyl Fluorides: Hydrogenation of Fluorinated Olefins
Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi.
Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för organisk kemi. University of KwaZulu-Natal, South Africa.ORCID-id: 0000-0002-1383-8246
Rekke forfattare: 42019 (engelsk)Inngår i: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 58, nr 27, s. 9282-9287Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The development of new general methods for the synthesis of chiral fluorine-containing molecules is important for several scientific disciplines. We herein disclose a straightforward method for the preparation of chiral organofluorine molecules that is based on the iridium-catalyzed asymmetric hydrogenation of trisubstituted alkenyl fluorides. This catalytic asymmetric process enables the synthesis of chiral fluorine molecules with or without carbonyl substitution. Owing to the tunable steric and electronic properties of the azabicyclo thiazole-phosphine iridium catalyst, this stereoselective reaction could be optimized and was found to be compatible with various aromatic, aliphatic, and heterocyclic systems with a variety of functional groups, providing the highly desirable products in excellent yields and enantioselectivities.

sted, utgiver, år, opplag, sider
2019. Vol. 58, nr 27, s. 9282-9287
Emneord [en]
alkenyl fluorides, asymmetric hydrogenation, iridium catalysis, N, P ligands, organofluorine compounds
HSV kategori
Identifikatorer
URN: urn:nbn:se:su:diva-171794DOI: 10.1002/anie.201903954ISI: 000476691200057PubMedID: 30995362OAI: oai:DiVA.org:su-171794DiVA, id: diva2:1345644
Tilgjengelig fra: 2019-08-26 Laget: 2019-08-26 Sist oppdatert: 2019-08-26bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Søk i DiVA

Av forfatter/redaktør
Ponra, SudiptaYang, JianpingAndersson, Pher G.
Av organisasjonen
I samme tidsskrift
Angewandte Chemie International Edition

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 23 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf