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Association of rotating shift work schedules and the use of prescribed sleep medication: A prospective cohort study
Stockholm University, Faculty of Social Sciences, Department of Psychology, Stress Research Institute. Swansea University, UK.ORCID iD: 0000-0002-8105-0901
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Number of Authors: 82021 (English)In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 30, no 6, article id e13349Article in journal (Refereed) Published
Abstract [en]

We examined whether working rotating shifts, with or without night work, is associated with the purchase of prescribed sleep medication, and whether the association is dependent on age. Data were obtained from a longitudinal cohort study of Finnish public sector employees who responded to questions on work schedule and background characteristics in 2000, 2004 and 2008. The data were linked to national register data on redeemed prescriptions of hypnotic and sedative medications, with up to 11 years of follow-up. Age stratified Cox proportional hazard regression models were computed to examine incident use of medication comparing two groups of rotating shift workers (those working shifts that included night shifts and those whose schedules did not include night shifts) with day workers who worked in a similar range of occupations. Shift work with night shifts was associated with increased use of sleep medication in all age groups, after adjustments for sex, occupational status, marital status, alcohol consumption, smoking and physical activity levels (hazard ratio [HR], [95% confidence interval, CI] 1.14 [1.01-1.28] for age group <= 39 years; 1.33 [1.19-1.48] for age group 40-49 years; 1.28 [1.13-1.44] for age group >= 50 years). Shift work without nights was associated with medication use in the two older age groups (HR [95% CI] 1.14 [1.01-1.29] and 1.17 [1.05-1.31] for age groups 40-49 years and >50 years, respectively). These findings suggest that circadian disruption and older age puts rotating shift workers, and especially those who work nights, at increased risk of developing clinically significant levels of sleep problems.

Place, publisher, year, edition, pages
2021. Vol. 30, no 6, article id e13349
Keywords [en]
age, circadian, hypnotics and sedatives, night work, work schedule
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Occupational Health and Environmental Health
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URN: urn:nbn:se:su:diva-195849DOI: 10.1111/jsr.13349ISI: 000661319800001PubMedID: 34128266OAI: oai:DiVA.org:su-195849DiVA, id: diva2:1588066
Available from: 2021-08-26 Created: 2021-08-26 Last updated: 2022-01-20Bibliographically approved

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Tucker, PhilipLeineweber, Constanze

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