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Cell-Penetrating Peptides and Transportan
Stockholm University, Faculty of Science, Department of Biochemistry and Biophysics. University of Tartu, Estonia.ORCID iD: 0000-0001-6107-0844
Number of Authors: 12021 (English)In: Pharmaceutics, ISSN 1999-4923, E-ISSN 1999-4923, Vol. 13, no 7, article id 987Article, review/survey (Refereed) Published
Abstract [en]

In the most recent 25-30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems. In this review, I present a brief introduction to the CPP area with selected recent achievements. This is followed by a nostalgic journey into the research in my own laboratories, which lead to multiple CPPs, starting from transportan and paving a way to CPP-based therapeutic developments in the delivery of bio-functional materials, such as peptides, proteins, vaccines, oligonucleotides and small molecules, etc.

Place, publisher, year, edition, pages
2021. Vol. 13, no 7, article id 987
Keywords [en]
transportan, cell-penetrating peptides, transfection, PepFect, NickFect
National Category
Pharmacology and Toxicology
Identifiers
URN: urn:nbn:se:su:diva-197354DOI: 10.3390/pharmaceutics13070987ISI: 000677369400001PubMedID: 34210007OAI: oai:DiVA.org:su-197354DiVA, id: diva2:1599174
Available from: 2021-09-30 Created: 2021-09-30 Last updated: 2022-02-25Bibliographically approved

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Langel, Ülo

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