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Psychological treatments for irritable bowel syndrome: a comprehensive systematic review and meta-analysis
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Number of Authors: 122023 (English)In: Cognitive Behaviour Therapy, ISSN 1650-6073, E-ISSN 1651-2316, Vol. 52, no 6, p. 565-584Article, review/survey (Refereed) Published
Abstract [en]

A wide range of psychological treatments have been found to reduce the symptoms of irritable bowel syndrome (IBS) but their relative effects are unclear. In this systematic review and meta-analysis, we determined the effects of psychological treatments for IBS, including subtypes of cognitive behavior therapy, versus attention controls. We searched 11 databases (March 2022) for studies of psychological treatments for IBS, reported in journal articles, books, dissertations, and conference abstracts. The resulting database comprised 9 outcome domains from 118 studies published in 1983–2022. Using data from 62 studies and 6496 participants, we estimated the effect of treatment type on improvement in composite IBS severity using random-effects meta-regression. In comparison with the attention controls, there was a significant added effect of exposure therapy (g = 0.52, 95% CI = 0.17–0.88) and hypnotherapy (g = 0.36, 95% CI = 0.06–0.67) when controlling for the pre- to post-assessment duration. When additional potential confounders were included, exposure therapy but not hypnotherapy retained a significant added effect. Effects were also larger with a longer duration, individual treatment, questionnaire (non-diary) outcomes, and recruitment outside of routine care. Heterogeneity was substantial. Tentatively, exposure therapy appears to be a particularly promising treatment for IBS. More direct comparisons in randomized controlled trials are needed. OSF.io identifier: 5yh9a.

Place, publisher, year, edition, pages
2023. Vol. 52, no 6, p. 565-584
Keywords [en]
functional gastrointestinal disorders, gut-brain interaction, psychotherapy, systematic review
National Category
Applied Psychology Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:su:diva-221273DOI: 10.1080/16506073.2023.2225745ISI: 001013937400001PubMedID: 37341454Scopus ID: 2-s2.0-85162683468OAI: oai:DiVA.org:su-221273DiVA, id: diva2:1799848
Note

This study was supported by Region Stockholm [ALF project], The Swedish Research Council [521-2013-2846], Jane and Dan Olsson foundation [4-1559/2013], and The Swedish Research Council for Health, Working life and Welfare [2014-4052].

Available from: 2023-09-25 Created: 2023-09-25 Last updated: 2024-01-15Bibliographically approved

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Johansson, Robert

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