This chapter considers current societal and organizational transitions that tend to affect the stress and health of individuals in paid employment. It is claimed that new stressors are substituted for those that characterized the industrial era, whereas stress in terms of a biopsychosocial process remains unchanged. New stressors emerge as a consequence of factors such as globalized economies and rapid diffusion of information and communication technology. Examples of emerging conditions are the fact that work may be performed anywhere and at any time, that increased speed of communication increases work intensity, and that parallell activities and frequent interruptions increases mental work load.