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Variance effective population size is affected by census size in sub-structured populations
Stockholm University, Faculty of Science, Department of Zoology, Population Genetics.ORCID iD: 0000-0003-3342-8479
Stockholm University, Faculty of Science, Department of Zoology, Population Genetics.ORCID iD: 0000-0001-9286-3361
Stockholm University, Faculty of Science, Department of Mathematics.ORCID iD: 0000-0003-2767-8818
Number of Authors: 32023 (English)In: Molecular Ecology Resources, ISSN 1755-098X, E-ISSN 1755-0998, Vol. 23, no 6, p. 1334-1347Article in journal (Refereed) Published
Abstract [en]

Measurement of allele frequency shifts between temporally spaced samples has long been used for assessment of effective population size (N-e), and this 'temporal method' provides estimates of N-e referred to as variance effective size (N-eV). We show that N-eV of a local population that belongs to a sub-structured population (a metapopulation) is determined not only by genetic drift and migration rate (m), but also by the census size (N-c). The realized N-eV of a local population can either increase or decrease with increasing m, depending on the relationship between N-e and N-c in isolation. This is shown by explicit mathematical expressions for the factors affecting N-eV derived for an island model of migration. We verify analytical results using high-resolution computer simulations, and show that the phenomenon is not restricted to the island model migration pattern. The effect of N-c on the realized N-eV of a local subpopulation is most pronounced at high migration rates. We show that N-c only affects local N-eV, whereas N-eV for the metapopulation as a whole, inbreeding (N-eI), and linkage disequilibrium (N-eLD) effective size are all independent of N-c. Our results provide a possible explanation to the large variation of N-e/N-c ratios reported in the literature, where N-e is frequently estimated by N-eV. They are also important for the interpretation of empirical N-e estimates in genetic management where local N-eV is often used as a substitute for inbreeding effective size, and we suggest an increased focus on metapopulation N-eV as a proxy for N-eI.

Place, publisher, year, edition, pages
2023. Vol. 23, no 6, p. 1334-1347
Keywords [en]
metapopulation effective size, migration, N-e estimation, sub-structured populations, variance effective population size
National Category
Zoology
Identifiers
URN: urn:nbn:se:su:diva-230731DOI: 10.1111/1755-0998.13804ISI: 000980575800001PubMedID: 37122118Scopus ID: 2-s2.0-85158059033OAI: oai:DiVA.org:su-230731DiVA, id: diva2:1868175
Available from: 2024-06-11 Created: 2024-06-11 Last updated: 2024-06-11Bibliographically approved

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Ryman, NilsLaikre, LindaHössjer, Ola

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