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Evaluation of a Micro-Channel Plate PMT in PET
Stockholms universitet, Naturvetenskapliga fakulteten, Fysikum. (Siemens Molecular Imaging)
(Siemens Molecular Imaging)
(Siemens Molecular Imaging)
Stockholms universitet, Naturvetenskapliga fakulteten, Fysikum. (Siemens Molecular Imaging)
2006 (engelsk)Inngår i: Nuclear Science Symposium Conference Record, 2006, IEEE, 2006, s. 2503-2505Konferansepaper, Publicerat paper (Fagfellevurdert)
Abstract [en]

The focus of this paper is the evaluation of micro-channel plate PMTs for PET detectors. Several properties of MCPs make them interesting for PET applications, such as fast time response, high spatial resolution, compact size, low susceptibility to magnetic fields, high gain and low power consumption. The preliminary tests in this paper are performed with the 51 mm times 51 mm square Burle 85011-501 assembly with 64 anodes (8 times 8). A new version of this MCP will be examined for the full paper. Initial measurements have been performed with a pulsed LASER (Hamamatsu Picosecond Light Pulser PLP-10 with M8903 Laser diode head). The engineering sample of the 85011 exhibited a time resolution of 26 ps. Further measurements will be performed, such as transit time measurements and timing measurements with scintillators. Single-photon timing measurements were presented earlier in [Ref. 1], from the old version as well as the suitability of the device in Cherenkov detectors in [Ref. 2]. For the full paper it is also planned to develop a circuit which allows lossless splitting of the anode signal.

sted, utgiver, år, opplag, sider
2006. s. 2503-2505
Identifikatorer
URN: urn:nbn:se:su:diva-31662ISBN: 1-4244-0560-2 (tryckt)OAI: oai:DiVA.org:su-31662DiVA, id: diva2:278544
Konferanse
Nuclear Science Symposium Conference
Tilgjengelig fra: 2009-11-26 Laget: 2009-11-23 Sist oppdatert: 2009-12-22bibliografisk kontrollert
Inngår i avhandling
1. Detector Considerations for Time-of-Flight in Positron Emission Tomography
Åpne denne publikasjonen i ny fane eller vindu >>Detector Considerations for Time-of-Flight in Positron Emission Tomography
2009 (engelsk)Doktoravhandling, med artikler (Annet vitenskapelig)
Abstract [en]

Positron-Emission-Tomography (PET) is a modern imaging technique in nuclear medicine providing quantitative 3D distribution of a radioactive tracer substance in the human body. The gamma-detector is the first link in the chain of components that constitutes a PET. It converts incoming radiation into optical light pulses, which are detected by photo multiplier tubes. Here the light is converted into electric pulses, to be further processed by the acquisition electronics. Improving detector sensitivity and resolution is of great value in research and in clinical practice.

The focus of this work is to improve the detector to give it time-of-flight (TOF) capabilities, in order to further improve sensitivity, which in turn leads to increased image quality, faster scan time and/or reduced dose exposure for the patient.

Image quality has improved over the years, but losses in image quality have been reported for heavy patients, due to increased attenuation, and more dispersed counts over a larger volume. Instrumentation limits are still significant in heavy patient images, but the incorporation of TOF information promises to alleviate some of the limitations.

In order to improve the timing resolution of the detector fast photo-multipliers and a novel scheme to extract the event timing trigger from a detector by using the summed dynode signal were investigated.

When designing new PET detectors, it is important to have detailed understanding and control of the light sharing mechanisms in the crystal arrays. Therefore it was necessary to perform optical simulations and single crystal light output measurements to derive a model for an LSO block detector.

Another way to improve the image quality is to use the depth-of-interaction (DOI) of the gamma ray within the detector. It is shown that a multi-layer phoswich detector comprised of LSO with different decay times and TOF capability, combines the benefits of TOF and DOI in one detector, maximizing the effective sensitivity gain.

sted, utgiver, år, opplag, sider
Stockholm: Department of Physics, Stockholm University, 2009. s. 78
Emneord
Positron Emission Tomography, Time of Flight, Depth of Interaction, LSO
HSV kategori
Forskningsprogram
medicinsk strålningsfysik
Identifikatorer
urn:nbn:se:su:diva-31587 (URN)978-91-7155-979-1 (ISBN)
Disputas
2010-01-08, FB52, AlbaNova universitetscentrum, Roslagstullsbacken 21, Stockholm, 10:00 (engelsk)
Opponent
Veileder
Merknad
At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 7: Submitted. Tilgjengelig fra: 2009-12-03 Laget: 2009-11-19 Sist oppdatert: 2009-12-22bibliografisk kontrollert

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