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Pharmacological evaluation of benzimidazole derivatives with potential antiviral and antitumor activity
Stockholms universitet, Naturvetenskapliga fakulteten, Institutionen för analytisk kemi.ORCID-id: 0000-0002-3862-8878
2012 (engelsk)Inngår i: Research on chemical intermediates (Print), ISSN 0922-6168, E-ISSN 1568-5675, Vol. 38, nr 9, s. 2523-2545Artikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [en]

In recent years the synthesis of benzimidazole and its derivatives has attracted the attention of many organic chemists because of the compounds' interesting biological activity and the crucial importance of the benzimidazole unit in the function of these biologically important molecules. Benzimidazole-based polyheterocyclic compounds have several interesting biological properties. Simple synthetic strategies leading to benzimidazole-based fused polyheterocyclic systems and the antiviral and anticancer biological activity of the compounds are surveyed in this review article.

sted, utgiver, år, opplag, sider
2012. Vol. 38, nr 9, s. 2523-2545
Emneord [en]
Benzimidazole derivatives, Combinatorial synthesis, Microwave-assisted synthesis, Heterocycles, Topoisomerase inhibitors, Protein kinase inhibitor, Antitumor, Antiviral
HSV kategori
Identifikatorer
URN: urn:nbn:se:su:diva-83028DOI: 10.1007/s11164-012-0569-yISI: 000310326400037OAI: oai:DiVA.org:su-83028DiVA, id: diva2:574415
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AuthorCount:3;

Tilgjengelig fra: 2012-12-05 Laget: 2012-12-03 Sist oppdatert: 2019-12-09bibliografisk kontrollert

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