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Cognitive outcome varies in adolescents born preterm, depending on gestational age, intrauterine growth and neonatal complications
Stockholms universitet, Samhällsvetenskapliga fakulteten, Psykologiska institutionen. Karolinska Institutet, Sweden.
Vise andre og tillknytning
2015 (engelsk)Inngår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 104, nr 3, s. 292-299Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Aim: The aim of this study was to investigate long-term cognitive outcome in a cohort of 18-year-olds born preterm and previously assessed at the age of 5.5.

Methods: We tested 134 adolescents born preterm with a very low birthweight of <1500g and 94 term-born controls with a comprehensive cognitive battery at 18years of age. The cohort was subdivided into 73 extremely preterm, 42 very preterm and 19 moderately preterm infants with gestational ages of 23-27, 28-31 and 32-36weeks, respectively. The moderately preterm group was dominated by adolescents born small for gestational age.

Results:Very preterm adolescents performed on a par with term-born controls. In contrast, extremely preterm adolescents displayed inferior results on all cognitive tests, more so if they had suffered neonatal complications. Moderately preterm adolescents scored lower than very preterm and full-term born adolescents, particularly on complex cognitive tasks.

Conclusion: Adolescents born at 28weeks of gestation or later, with appropriate birthweight and no perinatal complications, functioned like term-born peers at 18years of age. Extremely preterm birth per se posed a risk for long-term cognitive deficits, particularly executive deficits. Adolescents born moderately preterm but small for gestational age were at risk of general cognitive deficits.

sted, utgiver, år, opplag, sider
2015. Vol. 104, nr 3, s. 292-299
Emneord [en]
Adolescents, Long-term cognitive outcome, Medical complications, Preterm birth, Small for gestational age
HSV kategori
Identifikatorer
URN: urn:nbn:se:su:diva-115998DOI: 10.1111/apa.12864ISI: 000350062400022PubMedID: 25394225OAI: oai:DiVA.org:su-115998DiVA, id: diva2:801886
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AuthorCount:5;

Tilgjengelig fra: 2015-04-10 Laget: 2015-04-08 Sist oppdatert: 2022-03-23bibliografisk kontrollert

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Lundequist, AikoSmedler, Ann-Charlotte

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