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A Meta-analysis on the clinical efficacy and safety of optic capture in pediatric cataract surgery
Stockholms universitet, Samhällsvetenskapliga fakulteten, Statistiska institutionen. Capital University of Economics and Business, China.
Rekke forfattare: 22016 (engelsk)Inngår i: International Journal of Ophthalmology, ISSN 2222-3959, Vol. 9, nr 4, s. 590-596Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

AIM: To evaluate the clinical efficacy and safety of optic capture in pediatric cataract surgery. METHODS: Searches of peer-reviewed literature were conducted in PubMed, Embase and the Cochrane Library. The search terms were optic capture and cataract. The retrieval period ended in December 2014. Relevant randomized controlled trials (RCTs), case - control studies and cohort studies were included. Meta-analyses were performed. Pooled weighted mean differences and risk ratios with 95% confidence intervals were estimated. RESULTS: Ten studies involving 282 eyes were included, 5 of which were RCTs involving 194 eyes. The application of optic capture significantly reduced both opacification of the visual axis (RR: 0.12; 95% CI: 0.02 to 0.85; P=0.03) and occurrence of geometric decentration (RR: 0.09; 95% CI: 0.02 to 0.46; P=0.004). But it did not significantly affect best corrected visual acuity (BCVA) (WMD: -0.01; 95% CI: -0.07 to 0.05; P =0.75) and influence the occurrence of posterior synechia (RR: 1.53; 95% CI: 0.84 to 2.77; P=0.17). Deposits in the anterior intraocular lens were significantly increased in the optic capture group early after surgery (RR: 1.40; 95% CI: 1.05 to 1.86; P =0.02) and at the last follow-up (RR: 2.30; 95% CI: 1.08 to 4.92; P=0.03). The quality of the evidence was assessed as high. CONCLUSION: The application of optic capture significantly reduces opacification of visual axis and occurrence of geometric decentration but do not significantly improve BCVA with notable safety.

sted, utgiver, år, opplag, sider
2016. Vol. 9, nr 4, s. 590-596
Emneord [en]
optic capture, intraocular lens, pediatric cataract, secondary opacification, Meta-analysis
HSV kategori
Identifikatorer
URN: urn:nbn:se:su:diva-130643DOI: 10.18240/ijo.2016.04.20ISI: 000374276600020OAI: oai:DiVA.org:su-130643DiVA, id: diva2:932910
Tilgjengelig fra: 2016-06-02 Laget: 2016-05-27 Sist oppdatert: 2016-06-02bibliografisk kontrollert

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