Palladium-Catalyzed Oxidative Synthesis of a-Acetoxylated Enones from AlkynesShow others and affiliations
2016 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 55, no 19, p. 5824-5828Article in journal (Refereed) Published
Abstract [en]
We report a palladium-catalyzed oxidative functionalization of alkynes to generate -acetoxylated enones in one step. A range of functional groups are well-tolerated in this reaction. Mechanistic studies, including the use of O-18-labeled DMSO, revealed that the ketone oxygen atom in the product originates from DMSO.
Place, publisher, year, edition, pages
Wiley-VCH Verlagsgesellschaft, 2016. Vol. 55, no 19, p. 5824-5828
Keywords [en]
alkynes, enones, oxidation, palladium, sulfoxides
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:su:diva-131000DOI: 10.1002/anie.201600696ISI: 000375118500029PubMedID: 27060476OAI: oai:DiVA.org:su-131000DiVA, id: diva2:934882
Funder
EU, European Research CouncilSwedish Research CouncilBerzelii Centre EXSELENT2016-06-092016-06-092022-02-23Bibliographically approved