Synthesis, Characterization and Unusual Reactivity of Vinylbenziodoxolones-Novel Hypervalent Iodine Reagents
Number of Authors: 6
2016 (English)In: Chemistry - A European Journal, ISSN 0947-6539, E-ISSN 1521-3765, Vol. 22, no 45, 16066-16070 p.Article in journal (Refereed) Published
A novel type of hypervalent iodine(III) reagents, vinylbenziodoxolones (VBX), has been synthesized in a one-pot reaction from 2-iodobenzoic acid. VBX is bench stable, has been thoroughly characterized and the cyclic structure is supported by X-ray analysis. The reactivity of VBX was investigated in vinylation of nitrocyclohexane, and delivered vinylated products with opposite regioselectivity compared to acyclic vinyl(aryl) iodonium salts. The reagents could become a powerful tool in vinylation reactions under both metal-free and metal-catalyzed conditions.
Place, publisher, year, edition, pages
2016. Vol. 22, no 45, 16066-16070 p.
benziodoxolones, hypervalent compounds, structure analysis, synthetic methods, vinylation
IdentifiersURN: urn:nbn:se:su:diva-136921DOI: 10.1002/chem.201603955ISI: 000387132800014PubMedID: 27629653OAI: oai:DiVA.org:su-136921DiVA: diva2:1061677