Change search
ReferencesLink to record
Permanent link

Direct link
Perspectives in radiation biophysics: From radiation track structure simulation to mechanistic models of DNA damage and repair
Stockholm University, Faculty of Science, Department of Physics.
Show others and affiliations
Number of Authors: 5
2016 (English)In: Radiation Physics and Chemistry, ISSN 0969-806X, E-ISSN 1879-0895, Vol. 128, 3-10 p.Article in journal (Refereed) Published
Abstract [en]

In radiation targeted therapy and genetic risk estimation of low dose radiation protection there is a crucial need for full description of DNA damage response and repair (DDR) leading to cell death and cell mutation. We propose such a description can be arrived through realistic track-structure simulations together with mechanistic mathematical formulation of DDR and the availability of experimental data for testing the proof of principle. In this paper we review briefly first the state of the art in DNA damage and repair, and then the recent advances in the physics of track structure which represents an essential tool in radiation biophysics.

Place, publisher, year, edition, pages
2016. Vol. 128, 3-10 p.
Keyword [en]
DNA damage, DNA repair, Track structure, Cross sections, Monte Carlo
National Category
Chemical Sciences Mechanical Engineering Physical Sciences
URN: urn:nbn:se:su:diva-136041DOI: 10.1016/j.radphyschem.2016.05.005ISI: 000385325400002OAI: diva2:1061814
Available from: 2017-01-03 Created: 2016-11-29 Last updated: 2017-01-03Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Liljequist, David
By organisation
Department of Physics
In the same journal
Radiation Physics and Chemistry
Chemical SciencesMechanical EngineeringPhysical Sciences

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

ReferencesLink to record
Permanent link

Direct link