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Characterization of Lu-176 background in LSO-based PET scanners
Stockholm University, Faculty of Science, Department of Physics. Siemens Healthcare Molecular Imaging, USA; Karolinska Institute, Sweden; University of Tennessee, USA.
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Number of Authors: 7
2017 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 62, no 9, 3700-3711 p.Article in journal (Refereed) Published
Abstract [en]

LSO and LYSO are today the most common scintillators used in positron emission tomography. Lutetium contains traces of Lu-176, a radioactive isotope that decays beta(-) with a cascade of. photons in coincidence. Therefore, Lutetium-based scintillators are characterized by a small natural radiation background. In this paper, we investigate and characterize the Lu-176 radiation background via experiments performed on LSO-based PET scanners. LSO background was measured at different energy windows and different time coincidence windows, and by using shields to alter the original spectrum. The effect of radiation background in particularly count-starved applications, such as Y-90 imaging, is analysed and discussed. Depending on the size of the PET scanner, between 500 and 1000 total random counts per second and between 3 and 5 total true coincidences per second were measured in standard coincidence mode. The LSO background counts in a Siemens mCT in the standard PET energy and time windows are in general negligible in terms of trues, and are comparable to that measured in a BGO scanner of similar size.

Place, publisher, year, edition, pages
2017. Vol. 62, no 9, 3700-3711 p.
Keyword [en]
LSO background, randoms, PET
National Category
Medical Engineering Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:su:diva-143445DOI: 10.1088/1361-6560/aa68caISI: 000399098700001PubMedID: 28333041OAI: oai:DiVA.org:su-143445DiVA: diva2:1106486
Available from: 2017-06-07 Created: 2017-06-07 Last updated: 2017-06-07Bibliographically approved

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