Organizational changes are becoming a common response to financial and operational needs. The changes may be systematic and gradual or dramatic and sudden in an attempt to face various business demands. Different types of organizational changes are discussed in this chapter, focusing on the impact they may have on employees. One factor affecting employees' reactions to an organizational change is how the change is perceived and appraised – whether as a threat or as an opportunity. Individuals' health, well-being, and work-related attitudes may all be impacted, potentially carrying with it negative consequences for the organization as well as the individuals. Various individual and organizational factors that can influence the strength of the consequences of organizational change are also presented. These include individual factors such as personality, coping strategies, social status, and demographic characteristics as well as organizational factors such as organizational justice, opportunities for participation, and social support.