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What Ignites UCP1?
Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
Number of Authors: 22017 (English)In: Cell Metabolism, ISSN 1550-4131, E-ISSN 1932-7420, Vol. 26, no 5, p. 697-698Article in journal (Refereed) Published
Abstract [en]

We thought we knew how the heat-producing uncoupling protein 1 in brown adipose tissue was activated: by fatty acids released upon lipid droplet breakdown in the brown adipocytes. However, two studies in this issue (Schreiber et al., 2017; Shin et al., 2017) imply that this classical model may not be valid: heat can be produced in brown fat without intracellular lipolysis.

Place, publisher, year, edition, pages
2017. Vol. 26, no 5, p. 697-698
National Category
Biological Sciences Nutrition and Dietetics Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:su:diva-149826DOI: 10.1016/j.cmet.2017.10.012ISI: 000414541200002PubMedID: 29117542OAI: oai:DiVA.org:su-149826DiVA, id: diva2:1165463
Available from: 2017-12-13 Created: 2017-12-13 Last updated: 2018-01-13Bibliographically approved

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