This paper explores mixed methods research as a methodological approach integrating 1) philosophical and conceptual stances, 2) inquiry logics and 3) research methods. It is found to be pluralistic in that researchers may approach all three domains in a variety of ways, and eclectic in that any combination of data, methods and theories may be justified provided the research design is internally coherent, integrative and offers the best possibility of answering the research question. A brief overview of methodological writings in translation studies and an investigation of 10 sample theses indicate that theories and methods are often combined and adapted in the discipline, though usually without drawing on mixed methods research. It is argued that mixed methods research offers a methodological framework that is well attuned to contemporary translation studies research, not least by promoting interactive research design and providing a way to bridge the gap between different research traditions.