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Body mass index, sitting time, and risk of Parkinson disease
Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS).
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Number of Authors: 82018 (English)In: Neurology, ISSN 0028-3878, E-ISSN 1526-632X, Vol. 90, no 16, p. e1413-e1417Article in journal (Refereed) Published
Abstract [en]

Objective Causes of Parkinson disease are largely unknown, but recent evidence suggests associations with physical activity and anthropometric measures.

Methods We prospectively analyzed a cohort of 41,638 Swedish men and women by detailed assessment of lifestyle factors at baseline in 1997. Complete follow-up until 2010 was achieved through linkage to population-based registers. We used multivariable Cox proportional hazards models to estimate hazard ratios with 95% confidence intervals (CIs).

Results We identified 286 incident cases of Parkinson disease during follow-up. Multivariable adjusted hazard ratios were 1.06 (95% CI 0.76-1.47) for sitting time >= 6 vs <6 hours per day; and 1.13 (95% CI 0.60-2.12) for body mass index >= 30 vs < 25 kg/m(2). Results did not differ by sex.

Conclusions No association between prolonged sitting time per day or obesity and risk of Parkinson disease was found.

Place, publisher, year, edition, pages
2018. Vol. 90, no 16, p. e1413-e1417
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Public Health, Global Health, Social Medicine and Epidemiology
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URN: urn:nbn:se:su:diva-159171DOI: 10.1212/WNL.0000000000005328ISI: 000439129500007PubMedID: 29661903OAI: oai:DiVA.org:su-159171DiVA, id: diva2:1241731
Available from: 2018-08-24 Created: 2018-08-24 Last updated: 2018-08-24Bibliographically approved

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