Goals: To investigate the effectiveness of therapist-guided internet treatment for panic disorder (PD), and major depression (MD), in a routine care setting, the eMeistring clinic, within the public health care in Norway. Methods: Approximately 300 patients are included in two effectiveness studies, one per treatment (PD, MD). Assessment points are pretreatment, posttreatment and 6 months follow-up. Within group effect sizes, responder and remission rates are investigated. All analyses are Internet to treat. Results: Effect sizes for PD were large, d = 1.24 pre - post and 1.39 pre - 6 months follow-up. 56 % had recovered or were improved at posttreatment. Results for MD are preliminary and will be presented at the conference. Conclusion: Final conclusions will be presented at the conference. Results so far indicate that the treatments, after implementation into routine care in Norwegian public health care, are equally effective as in preceding effectiveness and randomized efficacy trials. The results so far thereby strengthen the notion that therapist guided Internet-based treatments are a viable alternative to other modes of treatment delivery.