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Nucleoside H-phosphonates and H-phosphonothioates: some chemical and stereochemical studies
Stockholm University, Faculty of Science, Department of Organic Chemistry.
1992 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Phosphonic acid's reaction towards sterically hindered acyl chlorides has been investigated. A new synthetic method for the synthesis of nucleoside Hphosphonate monoesters has been developed. Furthermore, a method for the synthesis of nucleoside H-phosphonothioate monoesters has also been developed. Some chemical and stereochemical aspects of ribonucleoside Hphosphonate and H-phosphonothioate synthesis have been studied. Three new reagents are described, which oxidize nucleoside H-phosphonates and Hphosphonothioates into corresponding phosphates, thiophosphates and selenophosphates.

Place, publisher, year, edition, pages
Stockholm: Stockholm University, 1992. , p. 54
Series
Chemical communications, ISSN 0366-5607 ; 1992:6
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:su:diva-165325Libris ID: 1497432ISBN: 91-7153-063-0 (print)OAI: oai:DiVA.org:su-165325DiVA, id: diva2:1282222
Public defence
1992-10-23, Hörsal G, Arrheniuslaboratorierna, Svante Arrhenius väg 16, Stockholm, 14:00
Note

Härtill 7 uppsatser

Available from: 2019-01-24 Created: 2019-01-24 Last updated: 2019-01-24Bibliographically approved

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