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Insomnia as a predictor of mental disorders: A systematic review and meta-analysis
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Number of Authors: 112019 (English)In: Sleep Medicine Reviews, ISSN 1087-0792, E-ISSN 1532-2955, Vol. 43, p. 96-105Article, review/survey (Refereed) Published
Abstract [en]

Previous research has identified insomnia as a predictor for the onset of depression. The aim of this meta-analysis is to investigate whether insomnia also predicts the onset of other mental disorders. Longitudinal studies were eligible for inclusion if they investigated insomnia at baseline (including nighttime- and daytime-symptoms) as a predictor of the later onset of psychopathology within a follow-up time-frame of at least 12 mo. Thirteen primary studies were included. The results suggest that insomnia is a significant predictor for the onset of depression (10 studies, OR 2.83, CI 1.55-5.17), anxiety (six studies, OR 3.23, CI 1.52-6.85), alcohol abuse (two studies, OR 1.35, CI 1.08-1.67, and psychosis (one study, OR 1.28, CI 1.03-1.59). The overall risk of bias in the primary studies was moderate. This meta-analysis provides evidence that insomnia increases the risk for psychopathology. A future research agenda should include more prospective studies using established diagnostic criteria, assessing insomnia at baseline and including long-term follow-up intervals evaluating a wider range of mental disorders. In addition, prospective long-term interventional studies investigating the efficacy of insomnia treatment for the prevention of mental disorders are called for.

Place, publisher, year, edition, pages
2019. Vol. 43, p. 96-105
Keywords [en]
Insomnia, Sleep, Psychopathology, Depression, Anxiety, Prevention, Risk factor
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:su:diva-166776DOI: 10.1016/j.smrv.2018.10.006ISI: 000456743300011PubMedID: 30537570OAI: oai:DiVA.org:su-166776DiVA, id: diva2:1295903
Available from: 2019-03-13 Created: 2019-03-13 Last updated: 2019-03-13Bibliographically approved

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Feige, BerndJansson-Fröjmark, Markus
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