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Cross-sectional associations between inflammation, sickness behaviour, health anxiety and self-rated health in a Swedish primary care population
Stockholm University, Faculty of Social Sciences, Stress Research Institute. Karolinska Institutet, Sweden.
Stockholm University, Faculty of Social Sciences, Stress Research Institute. Karolinska Institutet, Sweden.
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Number of Authors: 62019 (English)In: European journal of inflammation, ISSN 2058-7392, Vol. 17, article id 2058739219844357Article in journal (Refereed) Published
Abstract [en]

This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour (rho = 0.28, P < 0.001; rho = 0.42, P = 0.003) and high health anxiety (rho = 0.31, P < 0.001; rho = -0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men (rho = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women (rho = -0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety (rho = -0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

Place, publisher, year, edition, pages
2019. Vol. 17, article id 2058739219844357
Keywords [en]
cytokine, health anxiety, inflammation, self-rated health, sickness behaviour
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:su:diva-168327DOI: 10.1177/2058739219844357ISI: 000464963300001OAI: oai:DiVA.org:su-168327DiVA, id: diva2:1318108
Available from: 2019-05-26 Created: 2019-05-26 Last updated: 2019-05-26Bibliographically approved

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