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Dose-dependent enhancement of bioactivity by surface ZnO nanostructures on acid-etched pure titanium
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Number of Authors: 72019 (English)In: Advances in Applied Ceramics: Structural, Functional and Bioceramics, ISSN 1743-6753, E-ISSN 1743-6761, Vol. 118, no 3, p. 121-125Article in journal (Refereed) Published
Abstract [en]

Zinc (Zn) is found to be essential in biologic osseous functions, and deficiency of Zn may cause delayed skeletal growth and osteoporosis. Additionally, Zn-based coatings are reported to be effective to promote the bioactivity of implants. In this study, we employed the hydrothermal treatment to incorporate Zn into the surface of acid-etched pure Ti. The process was conducted in ammonia solution with an increased Zn precursor concentration (0.0002M, 0.002M and 0.02M, respectively). XPS analysis demonstrated that the nanostructures were composed of ZnO. Proliferation and alkaline phosphatase (ALP) activity of osteoblast-like SaOS-2 cells were enhanced dose-dependently, compared to those on the acid-etched pure Ti without ZnO nanostructures. This study addresses a favourable surface modification method to improve the bioactivity of implants.

Place, publisher, year, edition, pages
2019. Vol. 118, no 3, p. 121-125
Keywords [en]
ZnO, nanostructure, hydrothermal treatment, bone regeneration, titanium
National Category
Materials Engineering Materials Chemistry
Identifiers
URN: urn:nbn:se:su:diva-169051DOI: 10.1080/17436753.2018.1540449ISI: 000466772000001OAI: oai:DiVA.org:su-169051DiVA, id: diva2:1318448
Available from: 2019-05-27 Created: 2019-05-27 Last updated: 2019-05-27Bibliographically approved

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Shen, Zhijian
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Department of Materials and Environmental Chemistry (MMK)
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