Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Synthesis, Characterization and DFT Study of Bioactive 2-[(2-Methylpropanoyl)amino]propanoic Acid and Its Polymeric Tributyltin(IV) Derivative
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Show others and affiliations
Number of Authors: 72019 (English)In: ChemistrySelect, ISSN 2365-6549, Vol. 4, no 29, p. 8638-8644Article in journal (Refereed) Published
Abstract [en]

Tributyltin(IV) derivative (1) was synthesized by reacting the ligand (A(1)) {2-[(2-methylpropanoyl)amino]propanoic acid} with tributyltin(IV)chloride in presence of potassium hydroxide. The compounds were characterized by elemental analysis, FTIR and multinuclear (H-1, C-13 and Sn-119) NMR spectroscopy. The Sn-119 NMR data for (1) suggest that tin is five coordinated having trigonal bipyramidal molecular geometry. Molecular structures for (1) and (A(1)) were determined by single crystal X-ray analysis. Some new and novel structural features of the compounds, are reported first time. Tributyltin(IV) complex has distorted trigonal bipyramidal molecular geometry around tin in the solid state exhibiting single chain tetramer which may be ascribed as tetra-nuclear cage structure that is constructed from four tributyltin units and four ligand moieties. The tributyltin(IV) entities are bridged by one oxygen of the carboxylic group of one ligand and another oxygen of the amidic carbonyl of next ligand. The nature of Sn horizontal ellipsis O bond was analyzed with the help of natural bond orbital (NBO) analysis. The compounds were also screened in vitro for their anti-microbial and urease inhibition activities, and found some encouraging results.

Place, publisher, year, edition, pages
2019. Vol. 4, no 29, p. 8638-8644
Keywords [en]
DFT, Organotin(IV), Urease inhibition
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:su:diva-173172DOI: 10.1002/slct.201900869ISI: 000479139200041OAI: oai:DiVA.org:su-173172DiVA, id: diva2:1353560
Available from: 2019-09-23 Created: 2019-09-23 Last updated: 2019-09-23Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text

Search in DiVA

By author/editor
Taj, Muhammad BabarAyub, Rabia
By organisation
Department of Organic Chemistry
Chemical Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 2 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf