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Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C-C Bond Forming Cascade Reactions of Allenes
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Organic Chemistry. Mid Sweden University, Sweden.ORCID iD: 0000-0001-8462-4176
Number of Authors: 22020 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 85, no 8, p. 5428-5437Article in journal (Refereed) Published
Abstract [en]

An efficient palladium-catalyzed oxidative C-C bond forming cascade reaction of allenes involving a coupling between an enallene and an allenyne followed by a carbocyclization of the generated Pd-intermediate was developed. This cascade reaction afforded functionalized cross-conjugated polyenes. The enallene is initially activated by palladium and reacts with the allenyne to give the cross-conjugated polyenes.

Place, publisher, year, edition, pages
2020. Vol. 85, no 8, p. 5428-5437
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Chemical Sciences
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URN: urn:nbn:se:su:diva-191286DOI: 10.1021/acs.joc.0c00186ISI: 000607535100026PubMedID: 32207975OAI: oai:DiVA.org:su-191286DiVA, id: diva2:1538130
Available from: 2021-03-18 Created: 2021-03-18 Last updated: 2022-02-25Bibliographically approved

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Bäckvall, Jan-E.

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