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A simple model for the total number of SARS-CoV-2 infections on a national level
Stockholm University, Nordic Institute for Theoretical Physics (Nordita).ORCID iD: 0000-0002-7304-021X
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Number of Authors: 62021 (English)In: Epidemiology and Infection, ISSN 0950-2688, E-ISSN 1469-4409, Vol. 149, article id e80Article in journal (Refereed) Published
Abstract [en]

This study aimed to identify an appropriate simple mathematical model to fit the number of coronavirus disease 2019 (COVID-19) cases at the national level for the early portion of the pandemic, before significant public health interventions could be enacted. The total number of cases for the COVID-19 epidemic over time in 28 countries was analysed and fit to several simple rate models. The resulting model parameters were used to extrapolate projections for more recent data. While the Gompertz growth model (mean R-2 = 0.998) best fit the current data, uncertainties in the eventual case limit introduced significant model errors. However, the quadratic rate model (mean R-2 = 0.992) fit the current data best for 25 (89%) countries as determined by R-2 values of the remaining models. Projection to the future using the simple quadratic model accurately forecast the number of future total number of cases 50% of the time up to 10 days in advance. Extrapolation to the future with the simple exponential model significantly overpredicted the total number of future cases. These results demonstrate that accurate future predictions of the case load in a given country can be made using this very simple model.

Place, publisher, year, edition, pages
2021. Vol. 149, article id e80
Keywords [en]
Analysis of data, COVID-19, mathematical modelling
National Category
Public Health, Global Health and Social Medicine Mathematics
Identifiers
URN: urn:nbn:se:su:diva-194528DOI: 10.1017/S0950268821000649ISI: 000636848800001PubMedID: 33762052OAI: oai:DiVA.org:su-194528DiVA, id: diva2:1582765
Available from: 2021-08-03 Created: 2021-08-03 Last updated: 2025-02-20Bibliographically approved

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Lavoie, M. C.Brandenburg, AxelGorna, M. W.Merski, M.

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