Water as nucleophile in palladium-catalyzed oxidative carbohydroxylation of allene-substituted conjugated dienes
2007 (English)In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 129, no 46, 14120-14121 p.Article in journal (Refereed) Published
An efficient palladium(II)-catalyzed oxidative carbohydroxylation of allene-substituted conjugated dienes in aqueous media has been developed. The reaction is conducted employing p-benzoquinone as the stoichiometric reoxidant for the palladium or under aerobic conditions with essentially the same outcome. It is worth mentioning that this is the first example of a palladium(II)-catalyzed oxidation where a carbon−carbon bond is formed in water and also one of the few cases of nucleophilic attack by water on a (π-allyl)palladium complex.
Place, publisher, year, edition, pages
2007. Vol. 129, no 46, 14120-14121 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-11737DOI: 10.1021/ja075488jISI: 000251182000008OAI: oai:DiVA.org:su-11737DiVA: diva2:178256