Aging and brain degeneration
2005 (English)In: European Neuropsychopharmacology: Supplement 2, ISSN 0924-977X, Vol. 15, no Supplement 2, S101- p.Article in journal (Refereed) Published
Old persons, even middle-age persons, often complain about difficulties in remembering names, faces, birthdays, meetings and other happenings in daily life. A common worry is whether such events are signs of degenerative process as for example in dementia, or whether this forgetfulness is just an expression of normal aging. I will present an overview of what is known about memory development from middle-age adulthood to old, and to very old age in relation to biological markers. The role of several genes will be discussed, e.g. APOE, COMT, and some genes related to the immune system. Changes in brain activity will be related to some of the genes discussed. The structure of memory is discussed as a basis for why different genes may have various roles for different memory systems. As will be seen, different forms of memory seem to age at different rates. The relative contributions of environmental and genetic factors to the memory deficits that most people seem to experience as they grow older are evaluated.
Place, publisher, year, edition, pages
2005. Vol. 15, no Supplement 2, S101- p.
memory, aging, APOE, COMT
IdentifiersURN: urn:nbn:se:su:diva-13504DOI: doi:10.1016/S0924-977X(05)80226-3OAI: oai:DiVA.org:su-13504DiVA: diva2:180024