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Genetic influences on memory function in healthy individuals.
Stockholm University, Faculty of Social Sciences, Department of Psychology.
2005 (English)In: Abstracts of the Psychonomic Society, Vol. 10, 28-28 p.Article in journal (Refereed) Published
Abstract [en]

On the basis of a prospective cohort study on memory, health, and aging, it is proposed that genetic markers affect memory function in a way that is of interest for memory theory. Two markers related to the immune system (Comlement C3 and Haptoglibine) affect episodic memory, but not semantic memory. With demented and potentially demented people and people with cardiovascular disease, Apolipoprotein E (APOE) affects episodic memory- in particular, recall- and executive function. There is also a predictable decrease in episodic memory as a function of the dose of the malign ε4 allele of this gene. The COMT gene, related to the dopamine system, also affects episodic memory and executive function, but not other memory systems. The results obtained are discussed in terms of gene-gene and gene-environment interactions.

Place, publisher, year, edition, pages
2005. Vol. 10, 28-28 p.
Keyword [en]
memory, genetics, brain imaging
National Category
Psychology
Identifiers
URN: urn:nbn:se:su:diva-13508OAI: oai:DiVA.org:su-13508DiVA: diva2:180028
Available from: 2008-04-10 Created: 2008-04-10 Last updated: 2011-01-12Bibliographically approved

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