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QNet: an agglomerative method for the construction of phylogenetic networks from weighted quartets.
Stockholm University, Faculty of Science, Department of Biochemistry and Biophysics. Stockholms Bioinformatikcentrum. (Sonnhammer)
2007 (English)In: Mol Biol Evol, ISSN 0737-4038, Vol. 24, no 2, 532-8 p.Article in journal (Refereed) Published
Abstract [en]

We present QNet, a method for constructing split networks from weighted quartet trees. QNet can be viewed as a quartet analogue of the distance-based Neighbor-Net (NNet) method for network construction. Just as NNet, QNet works by agglomeratively computing a collection of circular weighted splits of the taxa set which is subsequently represented by a planar split network. To illustrate the applicability of QNet, we apply it to a previously published Salmonella data set. We conclude that QNet can provide a useful alternative to NNet if distance data are not available or a character-based approach is preferred. Moreover, it can be used as an aid for determining when a quartet-based tree-building method may or may not be appropriate for a given data set. QNet is freely available for download.

Place, publisher, year, edition, pages
2007. Vol. 24, no 2, 532-8 p.
Keyword [en]
Algorithms, Least-Squares Analysis, Models; Genetic, Models; Statistical, Phylogeny, Salmonella/genetics, Software
Identifiers
URN: urn:nbn:se:su:diva-14976ISI: 000243993100019PubMedID: 17119010OAI: oai:DiVA.org:su-14976DiVA: diva2:181496
Available from: 2008-11-12 Created: 2008-11-12 Last updated: 2011-01-11Bibliographically approved

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