Cell-penetrating peptide TP10 shows broad-spectrum activity against both Plasmodium falciparum and Trypanosoma brucei brucei
2008 (English)In: Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, E-ISSN 1098-6596, Vol. 52, no 9, 3414-3417 p.Article in journal (Refereed) Published
Malaria and trypanosomiasis are diseases which afflict millions and for which novel therapies are urgently required. We have tested two well-characterized cell-penetrating peptides (CPPs) for antiparasitic activity. One CPP, designated TP10, has broad-spectrum antiparasitic activity against Plasmodium falciparum, both blood and mosquito stages, and against blood-stage Trypanosoma brucei brucei.
Place, publisher, year, edition, pages
2008. Vol. 52, no 9, 3414-3417 p.
Biological Sciences Basic Medicine
IdentifiersURN: urn:nbn:se:su:diva-15051DOI: 10.1128/AAC.01450-07ISI: 000258667300056PubMedID: 18519720OAI: oai:DiVA.org:su-15051DiVA: diva2:181571