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Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
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2008 (English)In: Clin Cancer Res, ISSN 1078-0432, Vol. 14, no 17, 5476-83 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2008. Vol. 14, no 17, 5476-83 p.
Keyword [en]
Animals, Antineoplastic Combined Chemotherapy Protocols/*therapeutic use, Camptothecin/*analogs & derivatives/*pharmacology/therapeutic use, Cell Line; Tumor, Colonic Neoplasms/*drug therapy/genetics/pathology, DNA-Binding Proteins/*genetics, Humans, Mice, Mice; Nude, Microsatellite Instability, Mutation, Thymidine/*pharmacology/therapeutic use, Tumor Stem Cell Assay, Xenograft Model Antitumor Assays
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URN: urn:nbn:se:su:diva-16640ISI: 000259166000020PubMedID: 18765539OAI: oai:DiVA.org:su-16640DiVA: diva2:183160
Available from: 2008-12-19 Created: 2008-12-19 Last updated: 2011-01-10Bibliographically approved

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Helleday, Thomas
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Department of Genetics, Microbiology and Toxicology

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