Acyclic beta-amino acid catalyzed asymmetric anti-selective Mannich-type reactions
2007 (English)In: Tetrahedron: asymmetry, ISSN 0957-4166, E-ISSN 1362-511X, Vol. 18, no 9, 1033-1037 p.Article in journal (Refereed) Published
The ability of a primary amine containing acyclic beta(3)-amino acids to catalyze direct asymmetric anti-selective Mannich-type reactions is presented. The reactions are generally highly diastereo- and enantioselective to give the corresponding Mannich products with up to >19:1 dr (anti/syn) and 88-99% ee.
Place, publisher, year, edition, pages
2007. Vol. 18, no 9, 1033-1037 p.
IdentifiersURN: urn:nbn:se:su:diva-19291DOI: 10.1016/j.tetasy.2007.04.024ISI: 000247898000001OAI: oai:DiVA.org:su-19291DiVA: diva2:185815