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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Stockholm University.
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2005 (English)In: Nature, ISSN 1476-4687, Vol. 434, no 7035, 913-7 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2005. Vol. 434, no 7035, 913-7 p.
Keyword [en]
Animals, Antineoplastic Agents/*pharmacology/*therapeutic use, Azulenes, BRCA2 Protein/*deficiency/genetics, Benzodiazepines/pharmacology, Cell Line; Tumor, DNA Damage, DNA Repair, DNA Replication, Genes; BRCA2, Mice, Mice; Nude, Neoplasms/*drug therapy/enzymology/*genetics/pathology, Poly(ADP-ribose) Polymerases/*antagonists & inhibitors/deficiency/genetics/metabolism, Xenograft Model Antitumor Assays
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URN: urn:nbn:se:su:diva-20259PubMedID: 15829966OAI: oai:DiVA.org:su-20259DiVA: diva2:186785
Available from: 2007-11-23 Created: 2007-11-23 Last updated: 2011-01-12Bibliographically approved

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