Memory, genes, and brain imaging.
2006 (English)In: Aging, cognition and neuroscience., UNED Ediciones, Madrid , 2006, 43-46 p.Chapter in book (Refereed)
This chapter outlines and discusses potential risk factors for cognitive dysfunction and dementia. Illustrations of the arguments made are based on data from the Betula Study, which is a longitudinal, multi-cohort study being conducted in Umeå, Sweden. As a first step in these analyses of potential risk factors we have analyzed memory data by means of cluster analysis. We found that those who became demented belonged to one single cluster 15 years prior to dementia diagnosis. A second step in this search for early signs of dementia is to identify persons with the ε4 allele of the ApolipoproteinE gene. A third step described in the chapter is to assess brain activity by means of functional MR. Individuals with genetic risk of Alzheimer’s disease show a lower degree of brain activity than those with no such genetic risk.
Place, publisher, year, edition, pages
UNED Ediciones, Madrid , 2006. 43-46 p.
memory, genetics, brain imaging
IdentifiersURN: urn:nbn:se:su:diva-20314OAI: oai:DiVA.org:su-20314DiVA: diva2:186840