Vinylepoxides in Organic Synthesis
2006 (English)In: Aziridines and Epoxides in Organic Synthesis, Wiley-VCH: Weinheim , 2006, 315-347 p.Chapter in book (Refereed)
Vinylepoxides have become important intermediates in organic synthesis. The main reason for this is the development of selective methods for their subsequent transformations. As vinylepoxides are a special type of allylic electrophiles, it is necessary to control both the regioselectivity and the diastereoselectivity in their reactions with nucleophiles. The practical usefulness of vinylepoxides in synthesis will, however, always be dictated by their availability. Several methods for the asymmetric preparation of vinyloxiranes have been developed and it can be expected that the use of these compounds in organic synthesis will increase. This chapter starts with a discussion of the available techniques for preparing vinylepoxides, with emphasis on asymmetric methods. In the second part various transformations of vinylepoxides are summarized.
Place, publisher, year, edition, pages
Wiley-VCH: Weinheim , 2006. 315-347 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-20423ISBN: 978-3-527-31213-9OAI: oai:DiVA.org:su-20423DiVA: diva2:186949
FunderSwedish Research Council