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A comparison of radiobiological models for light ion therapy
Stockholm University, Faculty of Science, Medical Radiation Physics (together with KI).
Stockholm University, Faculty of Science, Medical Radiation Physics (together with KI).
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2007 (English)In: The 11th Workshop of Ion Beams in Biology and Medicine, 25-29 September 2007, Heidelberg, Germany, ISSN 1013-4506, p. 47 (2007), 2007Conference paper, Published paper (Other (popular science, discussion, etc.))
Abstract [en]

Treatment planning for light ion therapy requires development of radiobiological models describing the effects of light ion irradiation on cellular survival. The aim of this work is to compare some of these radiobiological models currently in use. The benchmark cell line used in these studies is an AA human melanoma cell line, irradiated in vitro under aerobic conditions by 60Co and 10B5+ ions of different values of linear energy transfer (40, 80, 125 and 160 keV/μm). The models used to analyze the data were: the standard linear-quadratic (LQ) model, the repairable-conditionally repairable (RCR) model, the probabilistic two-stage (P2S) model, Katz’s cellular track structure theory (TST), and the local effect model (LEM).

Place, publisher, year, edition, pages
2007.
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URN: urn:nbn:se:su:diva-21543OAI: oai:DiVA.org:su-21543DiVA: diva2:188070
Available from: 2007-12-12 Created: 2007-12-12Bibliographically approved

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