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Synthesis of fused bicyclic thioglycosides of N-acylated glucosamine as analogues of mycothiol
Stockholm University, Faculty of Science, Department of Organic Chemistry.
2007 In: Carbohydrate Research, Vol. 342, no 342, 1943–1946- p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2007. Vol. 342, no 342, 1943–1946- p.
Identifiers
URN: urn:nbn:se:su:diva-24570OAI: oai:DiVA.org:su-24570DiVA: diva2:197815
Note
Part of urn:nbn:se:su:diva-7191Available from: 2007-11-22 Created: 2007-11-14Bibliographically approved
In thesis
1. Synthesis of Structures Related to the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and to Mycothiol
Open this publication in new window or tab >>Synthesis of Structures Related to the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and to Mycothiol
2007 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis describes the synthesis of structures related to the capsular polysaccharide of Neisseria meningitidis serogroup A and the synthesis of analogues of mycothiol, a compound produced by Mycobacterium tuberculosis. The first part of the thesis describes the synthesis of structural elements present in the native capsular polysaccharide of Neisseria meningitidis serogroup A. In this part, an improved synthesis of 2-azido-2-deoxy-D-mannopyranose is included. The second part of the thesis describes the formation of stable C-phosphonate analogues related to the capsular polysaccharide. The last part outlines the formation of analogues of mycothiol, where the syntheses of a bicyclic analogue and a thioglycosidic analogue are described.

Place, publisher, year, edition, pages
Stockholm: Institutionen för organisk kemi, 2007. 44 p.
Keyword
Neisseria meningitidis, Capsular polysaccharide, Mycobacterium tuberculosis, Mycothiol
National Category
Organic Chemistry
Research subject
Organic Chemistry
Identifiers
urn:nbn:se:su:diva-7191 (URN)978-91-7155-540-3 (ISBN)
Public defence
2007-12-14, Magnélisalen, Kemiska övningslaboratoriet, Svante Arrhenius väg 12 A, Stockholm, 14:00
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Supervisors
Available from: 2007-11-22 Created: 2007-11-14Bibliographically approved

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