Enzyme- and ruthenium-catalyzed dynamic kinetic asymmetric transformation of 1,5-diols: Application to the synthesis of (+)-Solenopsin A
Stockholm University, Faculty of Science, Department of Organic Chemistry2009 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 74, no 5, 1988-1993 p.Article in journal (Refereed) Published
Dynamic kinetic asymmetric transformation (DYKAT) of 1,5-diols via combined lipase and ruthenium catalysis provides enantiomerically pure diacetates in high diastereoselectivity, which can serve as intermediates in natural product synthesis. This is demonstrated by the synthesis of (+)-Solenopsin A.
Place, publisher, year, edition, pages
2009. Vol. 74, no 5, 1988-1993 p.
IdentifiersURN: urn:nbn:se:su:diva-25571DOI: 10.1021/jo8025109ISI: 000263921700022OAI: oai:DiVA.org:su-25571DiVA: diva2:199994