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Organocatalytic enantioselective domino synthesis of highly functionalized cyclohexanes with an all-carbon quaternary stereocenter
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Organic Chemistry.
Stockholm University, Faculty of Science, Department of Physical, Inorganic and Structural Chemistry, Department of Structural Chemistry.
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2009 (English)In: Tetrahedron Letters, ISSN 0040-4039, E-ISSN 1359-8562, Vol. 50, no 26, 3458-3462 p.Article in journal (Refereed) Published
Abstract [en]

A highly enantioselective organocatalytic domino Michael/aldol reaction is presented. The reaction is catalyzed by chiral amines and gives access to highly functionalized cyclohexanes with one all-carbon quaternary stereocenter and multiple chiral stereocenters in high yields and 83–98% ee.

Place, publisher, year, edition, pages
Elsevier Ltd. , 2009. Vol. 50, no 26, 3458-3462 p.
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Organic Chemistry
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URN: urn:nbn:se:su:diva-28979DOI: 10.1016/j.tetlet.2009.02.209ISI: 000267070700091OAI: oai:DiVA.org:su-28979DiVA: diva2:228357
Available from: 2009-07-29 Created: 2009-07-29 Last updated: 2017-12-13Bibliographically approved

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Zhao, Gui-LingDziedzic, PawelEriksson, LarsCórdova, Armando
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