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Typing single polymorphic nucleotides in mitochondrial DNA as a way to access Middle Pleistocene DNA
Centro UCM-ISCIII de Evolucio´n y Comportamiento Humanos,C/Sinesio Delgado 4, 28029 Madrid, Spain.
Centro UCM-ISCIII de Evolucio´n y Comportamiento Humanos,C/Sinesio Delgado 4, 28029 Madrid, Spain.
Stockholm University, Faculty of Science, Department of Zoology.ORCID iD: 0000-0001-8270-7613
Departamento de Paleobiologı´a, Museo Nacional de Ciencias Naturales.
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2006 (English)In: Biology Letters, ISSN 1744-9561, Vol. 2, no 4, 601-603 p.Article in journal (Refereed) Published
Abstract [en]

In this study, we have used a technique designed to target short fragments containing informative mitochondrial substitutions to extend the temporal limits of DNA recovery and study the molecular phylogeny of Ursus deningeri. We present a cladistic analysis using DNA recovered from 400 kyr old U. deningeri remains, which demonstrates U. deningeri's relation to Ursus spelaeus. This study extends the limits of recovery from skeletal remains by almost 300 kyr. Plant material from permafrost environments has yielded DNA of this age in earlier studies, and our data suggest that DNA in teeth from cave environments may be equally well preserved.

Place, publisher, year, edition, pages
2006. Vol. 2, no 4, 601-603 p.
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URN: urn:nbn:se:su:diva-29718DOI: 10.1098/rsbl.2006.0515ISBN: 1744-9561 OAI: oai:DiVA.org:su-29718DiVA: diva2:234766
Available from: 2009-09-10 Created: 2009-09-10 Last updated: 2014-10-13Bibliographically approved

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