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The assembly of membrane proteins into complexes
Stockholm University, Faculty of Science, Department of Biochemistry and Biophysics.
2008 (English)In: Current opinion in structural biology, ISSN 0959-440X, E-ISSN 1879-033X, Vol. 18, no 4, 420-4 p.Article in journal (Refereed) Published
Abstract [en]

Protein complexes are a fundamental aspect of life in a membrane. It is therefore important to understand which proteins are assembled, and how the process of assembly is coordinated. To this end, a number of themes have emerged from the literature in recent years: first, membrane proteins assemble in an ordered, rather than a stochastic manner; second, they require chaperones to prevent unwanted interactions/aggregation; and third, they can be assembled into existing complexes. As these recurrent themes have emerged from studies on disparate complexes, they provide a general framework to understand the assembly of membrane proteins.

Place, publisher, year, edition, pages
2008. Vol. 18, no 4, 420-4 p.
Keyword [en]
Protein complexes, Membrane proteins
National Category
Natural Sciences
Research subject
Biophysics; Biochemistry
Identifiers
URN: urn:nbn:se:su:diva-27696DOI: 10.1016/j.sbi.2008.04.006ISI: 000259556000004PubMedID: 18539022OAI: oai:DiVA.org:su-27696DiVA: diva2:278399
Available from: 2009-11-25 Created: 2009-05-12 Last updated: 2017-12-12Bibliographically approved

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