Flow/sequential injection sample treatment coupled to capillary electrophoresis. A review
2009 (English)In: Analytica Chimica Acta, ISSN 0003-2670, E-ISSN 1873-4324, Vol. 648, 129-145 p.Article in journal (Refereed) Published
Various flow sample handling approaches coupled to capillary electrophoresis (CE) are reviewed, covering the research in this field in the 12 years since the milestone year of 1997, when practical interfaces to on-line couple flow injection (FI) and capillary electrophoresis were first developed independently by two research groups. Some previous attempts are also presented. Since 1997 a plethora of ingenious coupled systems have been developed. Although several reviews are available on various aspects of the topic, we have opted for a comprehensive overview of all FI-CE systems, as well as related and similar systems. This coupling has thus also led to the development of systems based on hybrids between the classical and microchip approaches. Truly microchip FI-CE systems are also included in this review. The developed systems have been used for various sample treatments, including on-line membrane-assisted sample treatment, column-based preconcentration, on-line derivatization and monitoring, to name just a few. The utility of coupling flow sampling to CE has been demonstrated in various practical applications that are discussed in detail. The current state-of-the-art and foreseeable future developments are also discussed.
Place, publisher, year, edition, pages
2009. Vol. 648, 129-145 p.
Flow injection analysis; Sequential injection analysis; Capillary electrophoresis; On-line coupling; Flow injection–capillary electrophoresis (FI–CE); Sequential injection analysis–capillary electrophoresis (SIA–CE); Sample pretreatment
Research subject Analytical Chemistry
IdentifiersURN: urn:nbn:se:su:diva-35124DOI: 10.1016/j.aca.2009.06.034ISI: 000269095000001OAI: oai:DiVA.org:su-35124DiVA: diva2:286458