Bag-SPE – A convenient extraction method for screening of pharmaceutical-residues in influent and effluent water from sewage treatment plants
2009 (English)In: Analytical and Bioanalytical Chemistry, ISSN 1618-2642, E-ISSN 1618-2650, Vol. 395, no 5, 1481-1489 p.Article in journal (Refereed) Published
Bag-SPE is a solid phase extraction (SPE) technique here applied to sample pharmaceutical residues in wastewater. The device consisting of 20 mg polystyrene-divinylbenzene (PS-DVB) enclosed in a woven polyester-fabric was immersed into 20 mL sample. Extraction of the analytes was performed under gentle rotation (25 rpm) until distribution equilibrium was achieved (4 hours). The extraction efficiency for thirteen pharmaceuticals was evaluated for the bag-SPE sampler compared to a conventional SPE cartridge (Oasis HLB). All analyzes were determined on an ultra performance liquid chromatography (UPLC) coupled to a quadrupole time of flight (QToF) mass spectrometer.
The detection limit of the bag-SPE technique for the analytes in wastewater ranged from 15-100 ng/L with recoveries between 20.7-58.2 % and ion-suppressions between 2.2-53.2 %. Although the extraction efficiencies were lower with the bag-SPE sampler compared to the SPE technique, the two methods showed similar detection limits due to the lower ion-suppression experienced with the bag-SPE. The results demonstrate that bag-SPE is an attractive alternative to the more, in terms of manual handling, demanding SPE-technique.
Place, publisher, year, edition, pages
Springer , 2009. Vol. 395, no 5, 1481-1489 p.
Bag-SPE, Solid phase extraction, Pharmaceuticals, Wastewater, UPLC-QToF
Research subject Applied Environmental Science
IdentifiersURN: urn:nbn:se:su:diva-35522DOI: 10.1007/s00216-009-3099-8ISI: 000270897000030OAI: oai:DiVA.org:su-35522DiVA: diva2:287448
ProjectsThis research was financially supported by European Union (European Commission, FP6 Contract No. 003956) “Novel Methods for Integrated Risk Assessment of Cumulative Stressors in the Environment” (NoMiracle) and by the Swedish research council Formas.