Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Maintenance and Manipulation in Working Memory: Differential Ventral and Dorsal Frontal Cortex fMRI Activity
Stockholm University, Faculty of Social Sciences, Department of Psychology.
Stockholm University, Faculty of Social Sciences, Department of Psychology.
Stockholm University, Faculty of Social Sciences, Department of Psychology.
Umeå universitet.
2009 (English)In: Acta Psychologica Sinica, ISSN 0439-755X, Vol. 41, no 11, 1054-1062 p.Article in journal (Refereed) Published
Abstract [en]

A verbal working memory protocol was designed and evaluated on a group of healthy younger adults in preparation for a large-scale functional magnetic resonance (fMRI) study on aging and memory. Letters were presented in two critical conditions: (i) maintenance, in which letters were to be memorized and kept in mind over a four second interval, and (ii) manipulation, in which letters were shifted forward in alphabetical order, and the new order was kept in mind. Analyses of fMRI data showed that the protocol elicited reliable activation in the frontal cortex, with manipulation producing more extensive activation patterns, both in whole-brain analyses and in predefined regions of interest (ROIs). There was also a distinction between dorsal and ventral lateral prefrontal regions, such that manipulation elicited more dorsolateral prefrontal activation. The protocol also elicited activation in various subcortical areas, previously associated with working-memory tasks. It was concluded that this working memory protocol is appropriate for investigating age-related changes in frontal-cortex functioning.

Place, publisher, year, edition, pages
Science Press , 2009. Vol. 41, no 11, 1054-1062 p.
Keyword [en]
frontal cortex, fMRI, working memory, maintenance, manipulation
National Category
Psychology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:su:diva-35784DOI: 10.3724/SP.J.1041.2009.01054OAI: oai:DiVA.org:su-35784DiVA: diva2:288006
Available from: 2010-01-20 Created: 2010-01-20 Last updated: 2010-10-29Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textFulltext

Search in DiVA

By author/editor
Pudas, SaraPersson, JonasNilsson, Lars-Göran
By organisation
Department of Psychology
Psychology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 45 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf