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Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop.
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2010 (English)In: Radiation research, ISSN 1938-5404, Vol. 173, no 2, 245-53 p.Article in journal (Refereed) Published
Abstract [en]

Radiation exposures from accidents, nuclear detonations or terrorist incidents are unlikely to be homogeneous; however, current biodosimetric approaches are developed and validated primarily in whole-body irradiation models. A workshop was held at the Armed Forces Radiobiology Research Institute in May 2008 to draw attention to the need for partial-body biodosimetry, to discuss current knowledge, and to identify the gaps to be filled. A panel of international experts and the workshop attendees discussed the requirements and concepts for a path forward. This report addresses eight key areas identified by the Workshop Program Committee for future focus: (1) improved cytogenetics, (2) clinical signs and symptoms, (3) cutaneous bioindicators, (4) organ-specific biomarkers, (5) biophysical markers of dose, (6) integrated diagnostic approaches, (7) confounding factors, and (8) requirements for post-event medical follow-up. For each area, the status, advantages and limitations of existing approaches and suggestions for new directions are presented.

Place, publisher, year, edition, pages
2010. Vol. 173, no 2, 245-53 p.
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URN: urn:nbn:se:su:diva-38300DOI: 10.1667/RR1993.1PubMedID: 20095857OAI: oai:DiVA.org:su-38300DiVA: diva2:309542
Available from: 2010-04-07 Created: 2010-04-07 Last updated: 2010-04-07Bibliographically approved

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Wojcik, Andrzej
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Department of Genetics, Microbiology and Toxicology

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