Change search
ReferencesLink to record
Permanent link

Direct link
Development of pigment-dispersing hormone-immunoreactive neurons in the American lobster: homology to the insect circadian pacemaker system?
Stockholm University, Faculty of Science, Department of Zoology.ORCID iD: 0000-0001-7815-4868
2009 (English)In: Cell and tissue research, ISSN 1432-0878, Vol. 335, no 2, 417-29 p.Article in journal (Refereed) Published
Abstract [en]

We have examined the development of pigment-dispersing hormone (PDH)-immunoreactive neurons in embryos of the American lobster Homarus americanus Milne Edwards, 1837 (Decapoda, Reptantia, Homarida) by using an antiserum against beta-PDH. This peptide is detectable in the terminal medulla of the eyestalks and the protocerebrum where PDH immunoreactivity is present as early as 20% of embryonic development. During ontogenesis, an elaborate system of PDH-immunoreactive neurons and fibres develops in the eyestalks and the protocerebrum, whereas less labelling is present in the deuto- and tritocerebrum and the ventral nerve cord. The sinus gland is innervated by PDH neurites at hatching. This pattern of PDH immunoreactivity has been compared with that found in various insect species. Neurons immunoreactive to pigment-dispersing factor in the medulla have been shown to be a central component of the system that generates the circadian rhythm in insects. Our results indicate that, in view of the position of the neuronal somata and projection patterns of their neurites, the immunolabelled medulla neurons in insects have homologous counterparts in the crustacean eyestalk. Since locomotory and other activities in crustaceans follow distinct circadian rhythms comparable with those observed in insects, we suggest that PDH-immunoreactive medulla neurons in crustaceans are involved in the generation of these rhythms.

Place, publisher, year, edition, pages
2009. Vol. 335, no 2, 417-29 p.
National Category
Research subject
URN: urn:nbn:se:su:diva-31136DOI: 10.1007/s00441-008-0728-zPubMedID: 19034522OAI: diva2:326384
Available from: 2010-10-06 Created: 2009-11-05 Last updated: 2014-10-13Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Dircksen, Heinrich
By organisation
Department of Zoology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 60 hits
ReferencesLink to record
Permanent link

Direct link